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Old 04-11-2018, 09:22 AM
Steve Steve is offline
Junior Member
Join Date: Apr 2018
Posts: 13
Default Re: Exocrine Pancreatic Insufficiency (EPI)

Originally Posted by jesse girl View Post
I believe EPI is the complete failure of the pancreas . Now i believe it includes no natural production on insulin anymore making a dog diabetic and the loss of digestive enzymes that the pancreas use to produce .

So you have to give a dog with EPI digestive enzymes when they eat . We have had EPI dogs on the forum and they did well once they figured the combination of enzymes food and insulin . I dont believe there are any active members at this time .

Is your dog EPI
Thank you all for your help. In response to "Jesse Girl" the information I have seen on EPI seems like the symptoms are very similar to diabetes. Though not trying to find the solution for long, I am a little frustrated with the treatment of the diabetes diagnosis thus far. I try to get Rusty some exercise time for two or three hour in the park every afternoon.

I hope this is not to long of a post, but I will try to give you the back ground over the past three months.

We have had little success with insulin doses and insulin changes. We started with 2 units of NPH every twelve hours. We progressed by one unit per day after a week with a glucose test at the vets in the AM prior to insulin and any food. The glucose levels remained 5 to 6 hundred during the morning tests. After numerous in office tests, I found out I could perform the test myself and I began coordinating with the vet over the phone. Once we reached 9 units, I performed a glucose curve (per vets instructions, ten blood tests). First test prior to insulin or food. For the next two hours, every thirty minutes followed by tests every two hours until the end of the day.

The levels were as follows: 473, 394, 369, 183, 72, 112, 137, 554, 579 (The last test was prior to food and insulin)

Let me add here, with nine units twice a day Rusty's behavior seemed to be improving. He had more energy, was consuming much less water and seemed a lot more lively.

The doctor did not like the wild swing in levels, but seemed more concerned about the low readings than all the high readings. After he consulted with a Urologist friend, he had us drop back to four units every twelve hours and a few days later wanted me to perform another curve.

Dropping to four units made a notable change in Rusty's energy level and water consumption.

The second curve was as follows: 604, 531, 496, 434, 444, 228, 131, 121, 236, 503, 676, 623 (the last two were two and four hours after evening meal and insulin injection).

After this curve (doctor was out of the office for a few days) I raised the level to 8 units every twelve hours. Upon the doctors return and his review of the curve, he wanted me to change insulin type and amount to Vetsulin, two units twice a day.

I noticed an immediate negative change in Rusty, as well as a body odor I had not noticed before. The doctor was out of the office once again and after five days and random blood test results between 400 plus and Hi (over 750 according to meter instructions) I discontinued the Vetsulin and reverted back to the NPH 9 units twice a day.

I sent an email to the doctor. I told him I had changed back to NPH 9 units twice a day and was trying to change Rusty's diet, though he was very rebellious to any modification in his diet. I told him Rusty was getting very annoyed by all the poking (which he hated). I told him his condition with the Vetsulin use turned immediately worse. I asked him if there could be a problem with the vial of NPH insulin. I questioned the accuracy of the Accu-Trak tester. My frustration with the methods of treatment and the negative results in Rusty's behavior was evident in the email. The doctor had mentioned me taking Rusty to a specialist, which I told him I could not afford.

Upon the doctors return, the doctor seemed upset with me and told me diabetic dogs need consistency and these changes were not helpful. He requested that I lower the level of NPH back to 4 units and discontinue glucose testing for a couple of weeks and then we can try another curve and see were we are at that time .

Tomorrow, April 12th will be two weeks. Since the change to 4 units Rusty's lifeless behavior and excessive water consumption has resumed and the body odor seems to be present at times. I have not spoken to the doctor for two weeks, but plan to performed glucose curve tomorrow. I purchased a new vial of NPH insulin and a new container of test strips. I don't have much optimism in he curve. I performed four tests yesterday.

Prior to food and insulin: 540
Prior to our walk and run in the park: 305
Following three hours of walking and running and a little digging: 683
Bed time 10 PM: Hi
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