Hi, Temporary Forumites,
Duncan, my 14-year-old Cocker, has been on trilostane since he was diagnosed with PDH 27 months ago. He originally started on 60 mg once a day, to which he responded immediately and well. Over the 2+ years since then, in response to regular stim testing, we've reduced his dose till now he's getting only 2 mg twice a day (i.e. 4mg a day total)! He went through a period last summer of gastro-intestinal problems that resulted in severe weight loss, despite having a pretty good appetite, but that seems to have leveled off - he's now about 22 lbs, down from his mature high weight of about 26 lbs and up from his low of last summer of 19 lbs. Apart from that period of weight loss, his energy, appetite, and quality of life have been great. Despite stims that keep trending lower, he's shown no signs of an Addisonian crash. So I'm writing not out of concern, but out of curiousity: have any of you experienced a similar reduction in the need for meds over the course of long-term trilostane treatment? I wonder if we're heading towards a time when he won't need the trilo anymore.
Thanks,
Carin
Duncan, my 14-year-old Cocker, has been on trilostane since he was diagnosed with PDH 27 months ago. He originally started on 60 mg once a day, to which he responded immediately and well. Over the 2+ years since then, in response to regular stim testing, we've reduced his dose till now he's getting only 2 mg twice a day (i.e. 4mg a day total)! He went through a period last summer of gastro-intestinal problems that resulted in severe weight loss, despite having a pretty good appetite, but that seems to have leveled off - he's now about 22 lbs, down from his mature high weight of about 26 lbs and up from his low of last summer of 19 lbs. Apart from that period of weight loss, his energy, appetite, and quality of life have been great. Despite stims that keep trending lower, he's shown no signs of an Addisonian crash. So I'm writing not out of concern, but out of curiousity: have any of you experienced a similar reduction in the need for meds over the course of long-term trilostane treatment? I wonder if we're heading towards a time when he won't need the trilo anymore.
Thanks,
Carin
Comment