Heartworm drug resistance: It's real!

[bgdavis]

New study that current macrocyclic lactone canine heartworm preventatives are not working as well as in the past. They believe that the worms are developing resistance.

http://news.vin.com/VINNews.aspx?articleId=28284

The macrocyclic lactone class of drugs in question comprises avermectin drugs (ivermectin and selamectin) and milbemycins (milbemycin oxime and moxidectin). These drugs are found in all commercial heartworm preventives, including: Heartgard (ivermectin), Tri-Heart Plus (ivermectin), Sentinel (milbemycin oxime), Revolution (selamectin), Advantage Multi (moxidectin), ProHeart6 (moxidectin), and Trifexis (milbemycin oxime).

[Patty]

Re: Heartworm drug resistance: It's real!

I just learned my uncle's golden was on Trifexis and has come up heartworm positive, though caught early.

[Abby's Mom]

Re: Heartworm drug resistance: It's real!

I still have Abby on Inteceptor... (remember I am the one that has 800 syringes in my garage)... as they are no longer making it. I am at a loss to what I will change her too. This makes me even more leery.

[Patty]

Re: Heartworm drug resistance: It's real!

Is Interceptor coming back on the market? I kept hearing it was that was last Aug. but then didn't have reason to research again.