Diabetes in Dogs: The k9diabetes.com Forum
 

Go Back   Diabetes in Dogs: The k9diabetes.com Forum > Canine Cushings - See http://www.k9cushings.com

Canine Cushings - See http://www.k9cushings.com The new www.K9Cushings.com is open! So this former temporary home is closed to new posts. Please go to www.k9cushings.com and check to see if your membership transferred there. It will remain viewable, however, until the transition to the new forum at http://www.k9cushings.com/forum is complete.

 
 
Thread Tools Search this Thread Display Modes
  #21  
Old 04-29-2009, 05:30 AM
Coolidge Coolidge is offline
Junior Member
 
Join Date: Apr 2009
Posts: 20
Default Re: Coolidge...

I know I sound like a nut case. Just want to make certain I have everything in order so there is no chance for skewing the tests.

I just remembered that the last ACTH test done at the end of Dec required fasting as well. (I'm pleading senior moment.) (None of the other ACTH tests were done with fasting.)

I just want an answer. I'm hoping this test will explain everything. The most expensive part of this is the shipping. Go figure.

I will keep everyone informed of the results of the tests.

Thank you everyone! I'd be lost without this board.
  #22  
Old 04-29-2009, 06:28 AM
Roxee'sDad's Avatar
Roxee'sDad Roxee'sDad is offline
Senior Member
 
Join Date: Apr 2009
Location: Middle TN
Posts: 136
Default Re: Coolidge...

Hi Becky,
Wow, what an epic you and Coolidge have been thru. I have nothing to add except good thoughts and prayers that you and Coolidge finally get a proper diagnosis and poor Coolidge gets a well deserved break.

Were all keeping our fingers and paws crossed.

John (Roxee's Dad)
  #23  
Old 04-29-2009, 08:59 AM
Squirt's Mom's Avatar
Squirt's Mom Squirt's Mom is offline
Senior Member
 
Join Date: Mar 2009
Location: Bauxite, AR
Posts: 175
Default Re: Coolidge...

Hi Becky,

You are doing just fine! Nut cases are always welcomed as I need all the company I can get!

I am sure UTK will be able to help Coolidge get the right diagnosis if this is Cushing's. That is one fine bunch of folks at UTK! Especially Dr O and his staff.

Squirt has had to fast for one of her ACTHs but not the others. I'm not sure what the difference is as to why they fast sometimes and not others. Seems like others have experienced this as well.

Like Ken said, hang real tough! We are hanging with you and are here anytime you need us.

Hugs,
Leslie and the girls
  #24  
Old 05-07-2009, 08:12 AM
Coolidge Coolidge is offline
Junior Member
 
Join Date: Apr 2009
Posts: 20
Default Re: Coolidge...

Well, it's been a week since they sent the samples to UT. I called my vet out of concern that no results have been forthcoming.

They called UT and they said they were "in the works". I'm glad I had this done, but I now know that they aren't the people I'd send any more samples to after her next loading phase. With Coolidge's low counts last time, we wouldn't have the luxury of waiting a week to put her on steroids.

Hopefully will hear back from them tomorrow or Monday. This waiting sorta, well, sucks - for both Coolidge and I. She's getting slower and her head hangs low. Would be nice to see her back at her perky self.

Thanks for all your support!
  #25  
Old 05-07-2009, 08:29 AM
stardeb55 stardeb55 is offline
Member
 
Join Date: Apr 2009
Posts: 62
Default Re: Coolidge...

I thought one of us had mentioned that it take 10-14 days to get UTK panel results back. How they handle their testing is they go through their freezers every Monday, collect up all sample received from the previous week, & start running panels on Monday. You are exactly right, this is why you don't send your routine stims to UTK. Routine stims need to be done by one of your regular vets so you get them back in a timely manner for med monitoring purposes. I'm contemplating having a repeat panel run on Harley at his next stim in July, but I will clearly indicate to my vet the stim is to be done locally, the remainder of the panel is to go to UTK. I also intend to make sure that UTK does not run a cortisol as I'm not going to pay twice for the same test.

Debbie

PS-Being a lab tech, I can understand why UTK has to batch their panels in this manner. I'm sure that the necessary supplies/reagents to do this testing are hideously expensive, so the more tests they run at once, the less the expense, & the less you have to pay as the owner. I shudder to think what a panel would cost, if they were being run one at at time.
  #26  
Old 05-11-2009, 12:55 PM
Coolidge Coolidge is offline
Junior Member
 
Join Date: Apr 2009
Posts: 20
Default Re: Coolidge...

The results are in. Just got a call from my vet. Cortisol levels were normal before and after.

However, the Hydroxyprogesterone and Progesteronewere elevated. My vet spoke with Dr. Oliver, who stated that Coolidge does in fact have ATYPICAL CUSHINGS.

He recommended a treatment of Flaxseed and if that didn't work, melatonin.

Now to research the atypical cushings.

I will post test results after I receive them. Thanks again for all your help!
  #27  
Old 05-11-2009, 01:23 PM
stardeb55 stardeb55 is offline
Member
 
Join Date: Apr 2009
Posts: 62
Default Re: Coolidge...

A couple of things. FSO & melatonin are usually used together. I can think of no one in this group who has an Atypical pup that is not using both of them, & that includes my Harley. This is per the treatment recommendation sheet from UTK. There should be one of these recommendation sheets that came with Coolidge's results. It would be a good idea if you could get a copy.

When it comes to the FSO, most of us are using some type of product that is purified lignans. Lignans are the active ingredient that works. The purified lignans allow you to make sure that you are giving a consistent, standardized dose, where the FSO is hit & miss about dosing. Also, a lot of Cushpups have liver issues, & adding the extra oil to their diet is not ideal. You might take a look a vitacost.com as I know they have a purified lignan. Several members are also using crushed flaxhulls from flaxhulls.com, but I'm not sure about the dosing on this product.

Debbie
  #28  
Old 05-11-2009, 01:45 PM
Lulusmom's Avatar
Lulusmom Lulusmom is offline
Interim CC
 
Join Date: Apr 2008
Posts: 101
Default Re: Coolidge...

Hi Becky,

I am so glad that you finally have a correct diagnosis. YAY!!!! Sorry for getting excited about your baby having Atypical Cushing's but I am pretty jazzed that it looks like he never had typical cushing's. That would certainly explain the apparent sensitivity to Lysodren. Having said that, I want to make it perfectly clear that not all dogs with normal cortisol are sensitive to the drug. The dogs involved in the original studies of the drug (then called o.p.-ddd) in the early 1940's were very healthy with normal adrenal activity. Many proved to be resistant to o.p.-ddd as they received very large doses of the drug for up to a year with no ill effects.

Please make sure that your vet gives you a copy of the treatment recommendations sheet that usually is attached to the panel results. I don't recall any other member advising that recommended treatment was solely flaxseed. Most of us atypical parents were given appropriate dosing for both melatonin and flaxseed oil with lignans. Since fso has a negligible amount of lignans, a lot of us have opted to leave the fso behind and go with purified lignans or the pressed flax hull lignans. Website links for the two latter products can be found on the utk website.

We'll be waiting to see the actual results of the panel and will be anxious to see how Coolidge responds to his new treatment. Just keep in mind that, often times, treatment with melotonin and/or lignans can take up to 3 to 4 months to see improvements so patience really is a virtue with atypical cushing's.

Glynda

P.S. I see that Debbie posted way ahead of me so sorry for the duplication. I'm at work and it really ticks me off when work gets in the way of my posts.

Last edited by Lulusmom; 05-11-2009 at 03:21 PM.
  #29  
Old 05-11-2009, 01:52 PM
Wylie's Mom's Avatar
Wylie's Mom Wylie's Mom is offline
Interim CC
 
Join Date: Apr 2009
Location: Fairfax, Virginia
Posts: 102
Default Re: Coolidge...

Atypical...That's great news!

Did you get a copy of the actual results? I agree with Debbie - just using one of the two doesn't make sense - get the actual treatment recommendations that UTK provided. They will list treatment option numbers and those numbers correspond to this list (on their website):

http://www.vet.utk.edu/diagnostic/en...hing's.pdf

-Susy
  #30  
Old 05-11-2009, 02:30 PM
Coolidge Coolidge is offline
Junior Member
 
Join Date: Apr 2009
Posts: 20
Default Re: Coolidge...

Well, my vet is snail mailing the results to me. I guess I could call and have them faxed to me.

She was pretty specific about what Dr. Oliver said. He wanted to start on the Flaxseed (powdered, not oil) and if that didn't cut back on Coolidges problems, to go to the Melatonin. He said that the last item to try was the Trilostane and only at maintenance doses (no loading). He agreed with the UW Vet school that Coolidge was hypersensitive to the lysodren and should be switched in that event.

However, I need your assistance in understanding Atypical Cushings. All I know is that instead of having excess cortisol (steroids) which left unchecked could lead to liver/kidney/heart problems; she has excess sex hormones. The first thing I thought of was, well, what kind of problem is that? But obviously there must be some ill effect from that as well. Can anyone share their insight with me?

The following link was interesting, but didn't tell me what I needed to know, at least in lay terms.


http://veterinarynews.dvm360.com/dvm.../detail/485128

Last edited by Coolidge; 05-11-2009 at 03:01 PM. Reason: added link...
 

Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -7. The time now is 10:38 AM.


Disclaimer -- The content on this site is provided for informational and educational purposes only. While we make every effort to present information that is accurate and reliable, the views expressed here are not meant to be a substitute for the advice provided by a licensed veterinarian. Please consult with your veterinarian for specific advice concerning the medical condition or treatment of your pet and before administering any medication or pursuing any course of treatment that you may read about on this site.

The views and opinions expressed by contributors to this forum are strictly their own and do not necessarily reflect the opinions and views of the owners, administrators, or moderators of this forum and the k9diabetes.com website.


Powered by vBulletin® Version 3.8.5
Copyright ©2000 - 2020, Jelsoft Enterprises Ltd.
Copyright 2009, 2010 k9diabetes.com. All rights reserved.